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Last Updated: Oct 14, 2026

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College Admission PMHNP Exam Syllabus Topics:

SectionWeightObjectives
Psychotherapy and Related Theories11%- Crisis intervention and stabilization
- Group, family, and individual therapy principles
- Evidence-based psychotherapy approaches
- Therapeutic frameworks and modalities
Scientific Foundation22%- Neuroanatomy, neurophysiology, neurochemistry
- Genetics, epigenetics, and developmental processes
- Pathophysiology of mental health disorders
- Psychopharmacology, pharmacokinetics, pharmacodynamics
Advanced Practice Skills27%- Screening, risk assessment, and safety evaluation
- Care coordination, interprofessional collaboration
- Health assessment, history taking, diagnostic reasoning
- Cultural competence, communication, and patient education
Diagnosis and Treatment22%- Diagnostic classification systems (DSM-5, ICD-10)
- Pharmacological management and monitoring
- Differential diagnosis across lifespan
- Biological, environmental, and lifestyle interventions
Ethics, Legal Principles, and Cultural Care17%- Advocacy, policy, and quality improvement
- Professional ethics, scope of practice, standards of care
- Legal regulations, confidentiality, informed consent
- Cultural, spiritual, and social determinants of health

College Admission American Nurses Credentialing Center: Adult Psychiatric-Mental Health Nurse Practitioner-Board Certified Sample Questions:

Question #1

Which statement accurately defines evidence-based practice?

  • A. The extent to which scientific research is generalizable to the real world
  • B. The process of developing specific predictions from general principles
  • C. Combining research, clinical knowledge, and patient preferences to reach a healthcare decision
  • D. The process of developing generalizations from specific observations
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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Question #2

Genes can account for differences in how individuals metabolize drugs. Genetic testing helps identify the presence of gene variants that may help determine the dosing of certain medications. Which of the following is an example of a gene test used in pharmacogenomics?

  • A. Phenotype
  • B. DNA
  • C. HLA-B
  • D. RNA
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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Question #3

Which of the following is least likely to be a comorbidity of PTSD?

  • A. Major depression
  • B. Dysthymia
  • C. Substance abuse or dependence
  • D. Psychosis
Reveal Solution  Discussion  0

Correct Answer: D  🗳️

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Question #4

A PMHNP refuses to perform a treatment requested by the patient because they believe it will cause harm. Which ethical theory supports this decision?

  • A. Teleological theory
  • B. Deontology
  • C. Virtue ethics
  • D. Utilitarianism
Reveal Solution  Discussion  0

Correct Answer: A  🗳️

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Question #5

Which federal agency regulates the introduction of new drugs in the United States?

  • A. National Institutes of Health
  • B. World Health Organization
  • C. Food and Drug Administration
  • D. Department of Health and Human Services
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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