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Last Updated: Jul 05, 2026

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Medical Council of Canada MCCQE Part 1 Sample Questions:

1. A 29-year-old woman presents to the sexually transmitted infection clinic with concerns regarding a copious vaginal discharge. Ten percent potassium hydroxide was used to confirm the diagnosis of which one of the following?

A) Group B streptococcus.
B) Trichomonas vaginalis.
C) Bacterial vaginosis.
D) Gonorrhea.
E) Chlamydia trachomatis.


2. You are a family physician caring for a healthy 60-year-old woman. Which one of the following preventative interventions is most useful?

A) Mammography every 2 years.
B) Fasting lipid profile every year.
C) Bone densitometry every 2 years.
D) Cervical cytology every year.
E) Fasting blood glucose every year.


3. A 24-year-old nulligravid woman presents to the office with an absence of menstruation since discontinuing her oral contraceptives 8 months ago. She previously had a regular menstrual cycle when taking oral contraceptives for the past 10 years but stopped because of headaches, which have only gotten worse since.
She also noticed mild breast discharge for the past several months. Which one of the following examination findings is most likely?

A) Presence of severe hirsutism
B) Low BMI
C) Abnormal visual field testing results
D) Nodular breast irregularities


4. A 37-year-old man presents with chronic back, neck, and shoulder pain following a workplace injury 4 years ago. He has a history of alcohol misuse and PTSD related to the incident. Current medications (acetaminophen, naproxen, amitriptyline, gabapentin) provide inadequate pain relief. He requests oxycodone after self-trialing it with temporary benefit. After history and physical assessment, which one of the following is the best next step?

A) Prescribing a short course of a short-acting opioid to be used only as needed.
B) Referring the patient to substance use and mental health support services.
C) Prescribing cannabis.
D) Ordering repeat imaging of the spine and shoulder to confirm the diagnosis.
E) Prescribing a low-dose, long-acting opioid and reassessing in 1 week for effectiveness.


5. You perform a literature search of journal articles on the effectiveness of a new antihypertensive for first-line treatment of people aged 35 to 50. You find reports of 4 good quality studies. Three of them show that statistically, the new drug is significantly more effective than the standard treatment, and one shows no difference. Before you conclude that the new antihypertensive is more effective in this group of patients, which one of the following concepts must be given consideration?

A) The power of the studies
B) Random error
C) Systematic error
D) Publication bias
E) Information bias


Solutions:

Question # 1
Answer: C
Question # 2
Answer: A
Question # 3
Answer: C
Question # 4
Answer: B
Question # 5
Answer: D

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