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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 42-year-old woman is diagnosed with deep vein thrombosis. Heparin therapy is initiated with
5,000 units as a single bolus injection, followed by an initial infusion rate of 1,000 units/h. The aPTT measured 6 hours later is >150 sec. Which of the following would be the most appropriate action at this time?

A) Administer protamine 5 mg, and decrease the infusion rate to 750 units/h.
B) Stop the infusion for one hour, then resume at 750 units/h.
C) Stop the infusion until the aPTT falls to <50 sec, and then resume at 750 units/h.
D) Continue the infusion at 1,000 units/h, since the aPTT was drawn too early and is not useful.

2. The Joint Commission requires accredited organizations to encourage which groups to report concerns about safety?

A) National special interest groups
B) Medical students rotating through organizations
C) Patients and families
D) Local specific disease support groups

3. In a case-control study of 285 subjects with Alzheimer's dementia and 1,080 control subjects, the number of patients with dyslipidemia was recorded for each group. Among the subjects with dyslipidemia who had taken statins, the odds ratio for developing dementia was 0.29 (95%CI,
0.13-0.63). Which of the following statements can accurately be made about the relationship between the taking of statins and the development of dementia in this study?

A) Taking statins was not associated with development of dementia.
B) Taking statins prevented development of dementia.
C) Taking statins was associated with a decreased risk of developing dementia.
D) Taking statins did not prevent development of dementia.

4. A pharmacotherapy specialist is evaluating a study that compared the effects of iron sucrose versus sodium ferric gluconate on ferritin levels in patients receiving hemodialysis. A significant difference was found between the groups. This study was conducted in a large academic center in Denmark; the specialist practices at a small rural hospital in Minnesota. Which of the following information in the paper will be most important in determining whether the study's results can be applied to the specialist's practice?

A) Inclusion/exclusion criteria
B) Statistical analysis
C) Randomization methods
D) Internal validity

5. A 35-year-old patient presents with symptoms consistent with acute pharyngitis. The patient reports no other illnesses, no known drug allergies, and a medical history significant for generalized anxiety disorder. The appropriate therapy should be determined by testing for which of the following?

A) Haemophilus influenzae
B) Streptococcus pneumoniae
C) Staphylococcus aureus
D) Group A Streptococcus

Solutions: